Professors Xavier Darzacq and Robert Tjian at the University of California, Berkeley have a long track record of discovering fundamental mechanisms of gene regulation in their academic labs and in biotech. In 2019 they teamed up with Kerry Kelly, attorney and accomplished biotech organizational expert, to launch Eikon Therapeutics. With over 400 employees and a world-class team of leaders, engineers, and scientists, Eikon is revolutionizing how live-cell imaging—pioneered by Darzacq—can guide drug discovery. This team has now pivoted to embark on a new venture, CxT Discovery, adding former coworker Jack Ferrie, founder and CEO of Sentauri Inc, with expertise in applying AI/ML to the life sciences. CxT was born out of this team’s enthusiasm for fundamental science as well as their frustration at the limitations imposed by current models of biopharma in developing more effective drug discovery programs.
Founder, Director
UC Berkeley professor and Eikon Therapeutics founder. Dr. Darzacq has experience in leading fundamental research on protein interactions regulating cellular processes as well as pharma technology development, guiding Eikon’s single molecule screening strategy as its CTO.
Founder
UC Berkeley Professor, former President of HHMI, and co-founder of Tularik, Nurix, Eikon and Lyterian with 40+ years of molecular biology and biochemistry research in gene regulation and stem cell differentiation. Dr. Tjian is also a Science Partner at The Column Group (2007-2009 & 2016-present).
Founder, Director, Head of Operations
20+ years of leadership experience in biotech and academia. Ms. Kelly has led legal and operational teams in a variety of life science organizations, including, Eikon Therapeutics, Cleave Therapeutics, Ambit Biosciences, the Scripps Research Institute,and Sugen Inc.
Founder
Biotech entrepreneur with a broad scientific background encompassing cell biology, chemistry, and artificial intelligence/machine learning (AI/ML). Dr. Ferrie is a founder and the CEO of Sentauri, Inc., a company that provides AI/ML solutions to accelerate research across biotech and pharma.
CxT Discovery is built on a model called FRO (Focused Research Organization) in which industry-like focus and resources combine with academia-like creativity and flexibility. CxT is structured around semi-independent research teams led by Investigators, each pursuing their own research and compound-discovery projects while cooperating closely to advance the organization’s mission. These teams have both strategic and operational support to maximize the efficiency and impact of their research.
Investigator
Previously Senior Scientist at Eikon Therapeutics. Dr. Driouchi brings deep microscopy knowledge as well as strong industry expertise in compound screening and assay development. He has led teams of scientists and engineers to execute discovery and drug-development projects.
Senior Research Associate
Biotechnology professional with 5 years of industry research experience with a focus on
molecular biology and protein engineering for oncology and viral targets. Experience with leading small teams
and working in a range of environments from start-ups to global pharma companies.
Associate Director of Portfolio and Strategy
Previously Swanson Fellow at The Column Group, where he sourced new therapeutic approaches and developed investment theses, leading to the formation of a seed-stage company. As a PhD student of Darzacq and Tjian, Dr. Karr focused on single-molecule microscopy and reconceptualizing mechanisms of transcription regulation.
VP of Operations
30+ years of operational experience in academia managing HR, Finance and Facilities for multiple research laboratories on the UC Berkeley campus and through the Howard Hughes Medical Institute.
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